American biologists James D. Watson and Francis Crick tell their friends that they have determined the chemical structure of DNA. The formal announcement takes place in April following publication in Nature magazine. In 1968, Watson writes The Double Helix, a non-fiction account of not only the discovery of the structure of DNA, but the personalities, conflicts and controversy surrounding the work.

In the United States, a conservative legal challenge to the nineteenth amendment to the U.S. Constitution establishing voting rights for women is rebuffed by the Supreme Court in Leser v. Garnett. The challenge was based partly on the idea of individual "states rights" to self determination. The failure of such reasoning as it applied to basic human rights created a framework for later states rights losses involving the denial of voting rights to African-Americans.

In New Orleans, The Original Dixieland Jass Band records the first ever jazz record for the Victor Talking Machine Company in New York. The band was frequently billed as the "Creators of Jazz", but in reality all the members had previously played in the Papa Jack Laine bands, a group of racially mixed performers who helped form the basis of Dixieland while playing under bandleader George Laine.